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Article

Congenic mice confirm that collagen X is required for proper hematopoietic development.

PloS one - 3 Mar 2010

Sweeney Elizabeth, Roberts Douglas, Corbo Tina, Jacenko Olena

Abstract excerpt

The link between endochondral skeletal development and hematopoiesis in the marrow was established in the collagen X transgenic (Tg) and null (KO) mice. Disrupted function of collagen X, a major hypertrophic cartilage matrix protein, resulted in skeletal and hematopoietic defects in endochondrally derived tissues. Manifestation of the disease phenotype was variable, ranging from perinatal lethality in a subset of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20209091
DOI: 10.1371/journal.pone.0009518
PMCID: PMC2831078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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