Article
Major histocompatibility complex susceptibility genes and immune thrombocytopenic purpura in Caucasian adults.
Hematology (Amsterdam, Netherlands) - 1 Apr 2002
Stanworth S J, Turner D M, Brown J, McCloskey D, Brown C, Provan D, Navarrete C V, Newland A C
Abstract excerpt
Immune thrombocytopenic purpura (ITP) is a heterogeneous disorder with wide variability in response rates to treatments including corticosteroids, splenectomy and intravenous immune globulins. The nature of the underlying predisposing causes for this autoimmune disorder are not known. We have HLA typed 71 adult Caucasian patients with chronic primary ITP, and compared the data with 750 control samples. In this...
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