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Article

The role of PTPN22 gene polymorphism in childhood immune thrombocytopenic purpura.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2011

Anis Shahira K, Abdel Ghany Eman A, Mostafa Naglaa O, Ali Aliaa A

Abstract excerpt

Immune thrombocytopenia is an autoimmune disorder characterized by antibody-mediated platelet destruction. A protein tyrosine phosphatase (PTPN22) present in lymphocytes is an important negative regulator of signal transduction for the T-cell receptor-MHC complex and has been associated with auto...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Purpura, Thrombocytopenic, Idiopathic

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Source

Identifiers

PMID: 21597364
DOI: 10.1097/MBC.0b013e328347b064

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21597364-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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