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Article

Molecular analysis of p53, MDM2, and H-ras genes in osteosarcoma and malignant fibrous histiocytoma of bone in patients older than 40 years.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2002

Kawaguchi Ken-ichi, Oda Yoshinao, Sakamoto Akio, Saito Tsuyoshi, Tamiya Sadafumi, Iwamoto Yukihide, Tsuneyoshi Masazumi

Abstract excerpt

Some investigators have reported that the histological features of osteosarcoma (OS) arising in elderly patients are different from those in younger patients; however, a molecular biologic study of OS in elderly patients has not been documented. In this study, 23 cases of OS (15 osteoblastic and 8 MFH-like types) and 18 cases of MFH of bone in patients 40 years of age or older were analyzed for mutation of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-mdm2

Source

Identifiers

PMID: 12181274
DOI: 10.1097/01.MP.0000024264.48690.EA

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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