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Article

Mutation of the DR5/TRAIL receptor 2 gene is infrequent in hepatocellular carcinoma.

Cancer letters - 26 Jul 2002

Jeng Yung-Ming, Hsu Hey-Chi

Abstract excerpt

Chromosome 8p21-22 is a frequent site of loss of heterozygosity in many types of cancer, including hepatocellular carcinoma (HCC). Tumor necrosis factor-related apoptosis-inducing ligand-receptor 2 (TRAIL-R2/DR5), a member of tumor necrosis factor receptor family, is mapped to chromosome 8p21-22. Mutations of TRAIL-R2 have been detected in lung cancer, breast cancer, head and neck cancer, and non-Hodgkin's...

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Share to Carcinoma, Hepatocellular
Share to Genes, Tumor Suppressor
Share to Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, TNF-Related Apoptosis-Inducing Ligand

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Source

Identifiers

PMID: 12175536
DOI: 10.1016/s0304-3835(02)00051-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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