Article
Sampling distribution of summary linkage disequilibrium measures.
1 May 2002
Abstract excerpt
The design of association studies is critically dependent upon the extent of linkage disequilibrium (LD) across different genomic regions, often summarised in terms of the mean absolute value of summary linkage disequilibrium measures. The two most commonly used measures are D' for estimating the magnitude or extent of LD, and Delta which is directly proportional to the power of LD mapping. We studied the...
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