Article
The distribution of long range admixture linkage disequilibrium in an African-American population.
Human heredity - 1 Jan 2002
Rybicki Benjamin A, Iyengar Sudha K, Harris Trent, Liptak Rachel, Elston Robert C, Sheffer Roberta, Chen Kang Mei, Major Marcie, Maliarik Mary J, Iannuzzi Michael C
Abstract excerpt
OBJECTIVES: To better understand the effect of admixture on long range linkage disequilibrium (LD), we characterized extended LD in gene-rich regions of an African-American population. METHODS: Approximately 290 cM of chromosomes 1, 3, 6, 11-17, 20 and 22 were scanned using 109 polymorphic microsatellite markers spaced an average of 3 cM apart. Disequilibrium between loci (D') was based on maximum-likelihood...
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