Article
Extensive long-range and nonsyntenic linkage disequilibrium in livestock populations: deconstruction of a conundrum.
Genetics - 1 Feb 2009
Lipkin E, Straus K, Stein R Tal, Bagnato A, Schiavini F, Fontanesi L, Russo V, Medugorac I, Foerster M, Sölkner J, Dolezal M, Medrano J F, Friedmann A, Soller M
Abstract excerpt
Great interest was aroused by reports, based on microsatellite markers, of high levels of statistically significant long-range and nonsyntenic linkage disequilibrium (LD) in livestock. Simulation studies showed that this could result from population family structure. In contrast, recent SNP-based studies of livestock populations report much lower levels of LD. In this study we show, on the basis of microsatellite...
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