Article
The effects of selected sampling on the transmission disequilibrium test of a quantitative trait locus.
Genetical research - 1 Apr 2002
Deng Hong-Wen, Li Jing
Abstract excerpt
We investigate how sampling of parents or children based on their extreme phenotypic values selected from clinical databases would affect the power of identification of quantitative trait loci (QTL) by a transmission disequilibrium test (TDT). We consider three selective sampling schemes based on the selection of phenotypic values of parents or children in nuclear families: (1) two children, one of extreme value,...
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