Article
A genome scan for loci influencing anti-atherogenic serum bilirubin levels.
European journal of human genetics : EJHG - 1 Sept 2002
Kronenberg Florian, Coon Hilary, Gutin Alexander, Abkevich Victor, Samuels Mark E, Ballinger Dennis G, Hopkins Paul N, Hunt Steven C
Abstract excerpt
Epidemiological studies have shown an association of decreased serum bilirubin levels with coronary artery disease. Two segregation analyses in large pedigrees have suggested a major gene responsible for high bilirubin levels occurring in about 12% of the population. Based on a recessive model from a previous segregation analysis, we performed a genome scan using 587 markers genotyped in 862 individuals from 48...
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