Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association meta-analysis for total serum bilirubin levels.

Human molecular genetics - 15 Jul 2009

Johnson Andrew D, Kavousi Maryam, Smith Albert V, Chen Ming-Huei, Dehghan Abbas, Aspelund Thor, Lin Jing-Ping, van Duijn Cornelia M, Harris Tamara B, Cupples L Adrienne, Uitterlinden Andre G, Launer Lenore, Hofman Albert, Rivadeneira Fernando, Stricker Bruno, Yang Qiong, O'Donnell Christopher J, Gudnason Vilmundur, Witteman Jacqueline C

Abstract excerpt

Variation in serum bilirubin is associated with altered cardiovascular disease risk and drug metabolism. We aimed to identify genetic contributors to variability in serum bilirubin levels by combining results from three genome-wide association studies (Framingham heart study, n = 3424; Rotterdam study, n = 3847; Age, Gene, Environment and Susceptibility-Reykjavik, n = 2193). Meta-analysis showed strong...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Bilirubin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Glucuronosyltransferase

Share to Liver-Specific Organic Anion Transporter 1

Share to Netherlands

Share to Organic Anion Transporters

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19414484
DOI: 10.1093/hmg/ddp202
PMCID: PMC2701336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association meta-analysis for total serum bilirubin levels.PMID 19414484Read ↗

Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant Article.Semantic proximity Read ↗

UGT1A1 is a major locus influencing bilirubin levels in African AmericansSemantic proximity Read ↗

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.Semantic proximity Read ↗

Genome-wide association of serum bilirubin levels in Korean population.Semantic proximity Read ↗

Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition.Semantic proximity Read ↗

Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean PopulationSemantic proximity Read ↗

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.Semantic proximity Read ↗

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.Semantic proximity Read ↗

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.Semantic proximity Read ↗

Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study.Semantic proximity Read ↗

Identifying Potential Therapeutic Applications and Diagnostic Harms of Increased Bilirubin Concentrations: A Clinical and Genetic Approach.Semantic proximity Read ↗

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.