Article
Angiotensin-converting enzyme genotype and outcome in pediatric IgA nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2002
Santos Noel M Delos, Ault Bettina H, Gharavi Ali G, Kritchevsky Stephen B, Quasney Michael W, Jackson Elizabeth C, Fisher Kimberly A, Woodford Susan Y, Mitchell Bonnie L, Gaber Lillian W, Arheart Kristopher L, Wyatt Robert J
Abstract excerpt
Angiotensin-converting enzyme (ACE) I/D polymorphism has been implicated as a genetic marker for progression of glomerular disease. Studies of ACE genotypes in adults with IgA nephropathy (IgAN) have yielded conflicting results. We performed ACE genotyping on 79 patients with IgAN diagnosed prior to age 18 years who had either progressed to end-stage renal disease (ESRD) or are now more than 5 years post biopsy....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.