Article
Angiotensin I-converting enzyme genotype significantly affects progression of IgA glomerulonephritis in an italian population.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jun 1999
Stratta P, Canavese C, Ciccone G, Barolo S, Dall'Omo A M, Fasano M E, Mazzola G, Berutti S, Fop F, Curtoni E S, Piccoli G
Abstract excerpt
To evaluate the role of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism in the progression of immunoglobulin A glomerulonephritis (IgA-GN), genotype distribution in 81 biopsy-proven cases of IgA-GN was studied. A logistic regression model showed that the risk for homozygous DD was not significantly elevated in patients with IgA-GN compared with healthy subjects (odds ratio = 1.16;...
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