Article
Impact of ACE I/D gene polymorphism on congenital renal malformations.
Pediatric nephrology (Berlin, Germany) - 1 Apr 2001
Hohenfellner K, Wingen A M, Nauroth O, Wühl E, Mehls O, Schaefer F
Abstract excerpt
To investigate the role of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism on prevalence and progression of disease in children with chronic renal failure (CRF), we determined the ACE I/D genotype in 95 children with CRF due to renal malformations (hypo-/dysplasia, obstructive uropathy, reflux nephropathy; n = 59), other congenital or hereditary diseases (n = 23), or acquired...
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