Article
Donor and recipient ACE I/D genotype are associated with loss of renal function in children following renal transplantation.
Pediatric transplantation - 1 Mar 2011
Büscher Rainer, Nagel Dominik, Finkelberg Ilja, Büscher Anja K, Wingen Anne-Margret, Kranz Birgitta, Vester Udo, Hoyer Peter F
Abstract excerpt
Genetic polymorphisms of the RAS correlate with allograft function. We therefore analyzed common RAS polymorphisms in kidney donors and in children following RTx to determine the relationship between genotype and decline in GFR, blood pressure, and LVM. A total of 107 children who underwent RTx were included: 70 male, 37 female, mean age 8.8±4.9 yr, mean follow up 5.4 yr. The following RAS polymorphisms were...
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