Article
Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2002
Yamasawa Kunihiro, Nio Yoshinori, Dong Ming, Yamaguchi Kazushige, Itakura Masayuki
Abstract excerpt
PURPOSE: The growth arrest and DNA damage-inducible 45 gene (GADD45a) is one of the downstream mediators of the p53 gene that stimulates DNA excision repair. The present study was designed to assess the clinicopathological significance of GADD45a and p53 in resectable invasive ductal carcinomas (IDCs) of the pancreas. EXPERIMENTAL DESIGN: This study included 72 pancreatic IDC patients who received surgery between...
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