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Article

The GADD45A (1506T>C) Polymorphism Is Associated with Ovarian Cancer Susceptibility and Prognosis.

PloS one - 1 Jan 2015

Yuan Cunzhong, Liu Xiaoyan, Liu Xiaolin, Yang Ning, Liu Zhenping, Yan Shi, Shen Keng, Kong Beihua

Abstract excerpt

GADD45A (growth arrest and DNA damage 45 A) is the first stress-inducible gene identified to be a target of p53. However, no studies to date have assessed variants of the GADD45 gene and their potential relationship to tumor susceptibility. We investigated the association of the GADD45A (1506T>C) polymorphism with ovarian cancer development in 258 ovarian cancer patients and 332 age-matched healthy women as...

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Identifiers

PMID: 26422378
DOI: 10.1371/journal.pone.0138692
PMCID: PMC4589388

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