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Article

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses.

Human molecular genetics - 15 Aug 2002

Sipione Simonetta, Rigamonti Dorotea, Valenza Marta, Zuccato Chiara, Conti Luciano, Pritchard Joel, Kooperberg Charles, Olson James M, Cattaneo Elena

Abstract excerpt

Gene expression studies conducted with mouse models of Huntington's disease (HD) have revealed profound modifications in gene transcription. However, the complexity of in vivo tissue hampers definition of very early transcriptional modifications and does not allow discrimination between cell-autonomous changes and those resulting from intercellular activity processes. To identify early, cell-autonomous...

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PMID: 12165557
DOI: 10.1093/hmg/11.17.1953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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