The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake.

doi:10.1046/j.1523-5378.2002.00088.x

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Article

The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake.

Helicobacter - 1 Aug 2002

van Vliet Arnoud H M, Stoof Jeroen, Vlasblom Ronald, Wainwright Stuart A, Hughes Nicola J, Kelly David J, Bereswill Stefan, Bijlsma Jetta J E, Hoogenboezem Theo, Vandenbroucke-Grauls Christina M J E, Kist Manfred, Kuipers Ernst J, Kusters Johannes G

Abstract excerpt

BACKGROUND: Availability of the essential nutrient iron is thought to vary greatly in the gastric mucosa, and thus the human gastric pathogen Helicobacter pylori requires regulatory responses to these environmental changes. Bacterial iron-responsive regulation is often mediated by Ferric Uptake Regulator (Fur) homologs, and in this study we have determined the role of H. pylori Fur in regulation of H. pylori iron...

Topics

Bacterial Outer Membrane Proteins
Bacterial Proteins
Biological Transport
Carrier Proteins
Culture Media
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Helicobacter pylori
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Iron

Lac Operon

Mutation

Promoter Regions, Genetic

Receptors, Cell Surface

Recombinant Fusion Proteins

Repressor Proteins

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 12165031
DOI: 10.1046/j.1523-5378.2002.00088.x

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