Article
Regulation of ferritin-mediated cytoplasmic iron storage by the ferric uptake regulator homolog (Fur) of Helicobacter pylori.
Journal of bacteriology - 1 Nov 2000
Bereswill S, Greiner S, van Vliet A H, Waidner B, Fassbinder F, Schiltz E, Kusters J G, Kist M
Abstract excerpt
Homologs of the ferric uptake regulator Fur and the iron storage protein ferritin play a central role in maintaining iron homeostasis in bacteria. The gastric pathogen Helicobacter pylori contains an iron-induced prokaryotic ferritin (Pfr) which has been shown to be involved in protection against metal toxicity and a Fur homolog which has not been functionally characterized in H. pylori. Analysis of an isogenic...
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