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Iron-Responsive Regulation of the<i>Helicobacter pylori</i>Iron-Cofactored Superoxide Dismutase SodB Is Mediated by Fur

18 May 2005

Abstract excerpt

Maintaining iron homeostasis is a necessity for all living organisms, as free iron augments the generation of reactive oxygen species like superoxide anions, at the risk of subsequent lethal cellular damage. The iron-responsive regulator Fur controls iron metabolism in many bacteria, including the important human pathogen Helicobacter pylori, and thus is directly or indirectly involved in regulation of oxidative...

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PMID: 15901691
DOI: 10.1128/jb.187.11.3687-3692.2005

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Iron-Responsive Regulation of the<i>Helicobacter pylori</i>Iron-Cofactored Superoxide Dismutase SodB Is Mediated by FurPMID 15901691Read ↗

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Random and site-specific mutagenesis of the Helicobacter pylori ferric uptake regulator provides insight into Fur structure-function relationships.Semantic proximity Read ↗

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