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Article

Rescue of HIV-1 receptor function through cooperation between different forms of the CCR5 chemokine receptor.

The Journal of biological chemistry - 18 Oct 2002

Chelli Maurice, Alizon Marc

Abstract excerpt

Interaction of the human immunodeficiency virus (HIV-1) envelope glycoproteins with the CCR5 chemokine receptor, a G-protein-coupled receptor, triggers a membrane fusion process and virus entry. Cooperation for HIV-1 receptor activity was observed when two forms of CCR5 were coexpressed, either the wild-type (WT) receptor and a defective mutant with deletion of the amino-terminal (NT) extracellular domain or the...

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Source

Identifiers

PMID: 12154092
DOI: 10.1074/jbc.M205394200

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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