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Article

The effect of bacillus Calmette-Guérin immunization depends on the genetic predisposition to Th2-type responsiveness.

American journal of respiratory cell and molecular biology - 1 Aug 2002

Hylkema Machteld N, Timens Wim, Luinge Marjan, Van Der Werf Nienke, Hoekstra Maarten O

Abstract excerpt

The aim of this study was to investigate whether the effect of bacillus Calmette-Guérin (BCG) immunization on ovalbumin-induced allergic inflammation in a rat model depends on the genetic predisposition to react with a T helper cell (Th) 2-type cytokine response. This study was performed in an inbred Th2-predisposed "asthma prone" rat strain (brown Norway [BN]) and in an outbred nonpredisposed strain (Sprague...

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Identifiers

PMID: 12151317
DOI: 10.1165/ajrcmb.27.2.4735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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