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Article

Genetic background determines the nature of immune responses and experimental immune-mediated blepharoconjunctivitis (EC).

Current eye research - 1 Feb 1999

Yoshida O, Yoshida H, Iwamoto H, Nishino K, Fukushima A, Ueno H

Abstract excerpt

PURPOSE: Experimental immune-mediated blepharoconjunctivitis (EC) was induced in Lewis rats by immunization with ovalbumin (OVA) in complete Freund's adjuvant (CFA) or aluminum hydroxide [Al(OH)3]. To investigate the affect of genetic factors on the susceptibility of EC, we tested different strains of rats for the development of EC. METHODS: Lewis and Brown Norway (BN) rats were immunized once with 100 microg of...

Topics

Aluminum Hydroxide
Animals
Antibody Formation
Blepharitis
Conjunctivitis
Cytokines
Disease Models, Animal
Enzyme-Linked Immunosorbent Assay
Freund's Adjuvant
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunity, Cellular

Immunoglobulin E

Immunoglobulin G

Lymph Nodes

Lymphocyte Activation

Male

Ovalbumin

Rats

Source

Identifiers

PMID: 10223655
DOI: 10.1076/ceyr.18.2.117.5383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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