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Article

The strength of the OVA-induced airway inflammation in rats is strain dependent.

Clinical and experimental immunology - 1 Sept 2002

Hylkema M N, Hoekstra M O, Luinge M, Timens W

Abstract excerpt

To examine the influence of genetics on the OVA-induced allergic inflammatory response in lungs we compared rats that are genetically Th2-predisposed (Brown Norway, inbred) or not genetically predisposed (Sprague Dawley, outbred). Rats were sensitized with ovalbumin (OVA) and challenged four weeks later with OVA aerosol. Eighteen hours after challenge, lung tissue was studied for evaluation of numbers of...

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Identifiers

PMID: 12197878
DOI: 10.1046/j.1365-2249.2002.01938.x
PMCID: PMC1906482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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