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Article

Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer.

Cancer research - 1 Apr 2001

Lukas J, Gao D Q, Keshmeshian M, Wen W H, Tsao-Wei D, Rosenberg S, Press M F

Abstract excerpt

mdm2 is part of a complex mechanism that regulates the expression of p53 as well as the function of Rb, p19ARF, and other genes. In humans, mdm2 dysregulation is associated with gene amplification. This study was undertaken to characterize altered mdm2 expression in a cohort of 38 invasive breast cancers and 9 normal breast specimens. Reverse-transcription PCR with primers spanning the entire open reading frame...

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PMID: 11306511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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