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Article

Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility.

Journal of autoimmunity - 1 Jun 2002

Cheunsuk Saijai, Sparks Rachel, Noveroske Janice K, Hsu Tom, Justice Monica J, Gershwin M Eric, Gruen Jeffrey R, Bowlus Christopher L

Abstract excerpt

PRSS16 is a serine protease specifically expressed by epithelial cells in the thymic cortex. The human gene is encoded on 6p21.3-p22 where recent linkage analysis has identified an association with insulin dependent diabetes mellitus (IDDM) susceptibility independent of HLA-DR3. To further investigate its potential role in autoimmunity, we characterized the mouse orthologue, Prss16. The genomic structure of...

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Source

Identifiers

PMID: 12144812
DOI: 10.1006/jaut.2002.0593

Genes

PRSS16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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