Article
Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos.
Nature - 1 Dec 1994
Hooper J E
Abstract excerpt
Two secreted proteins, Wingless and Hedgehog, instruct cell fates within the segmented epidermis of Drosophila embryos (reviewed in ref. 5). Wingless (Wg) is expressed by the most posterior cells in each parasegment; Hedgehog (Hh) is expressed in the most anterior cells of the next parasegment. Immediately after gastrulation, the two cell types are mutually dependent. Local Wg signalling stabilizes Hh expression...
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