Article
Role of hlx1 in zebrafish brain morphogenesis.
The International journal of developmental biology - 1 Jan 2002
Hjorth Jensen T, Connor Robin M, Key Brian
Abstract excerpt
hlx1 is a related homeobox gene expressed in a dynamic spatiotemporal expression pattern during development of the zebrafish brain. The homologues of hlx1, mouse dbx1 and Xenopus Xdbx, are known to play a role in the specification of neurons in the spinal cord. However, the role of these molecules in the brain is less well known. We have used two different approaches to elucidate a putative function for hlx1 in...
Topics
- Animals
- Axons
- Body Patterning
- Brain
- Cloning, Molecular
- DNA, Complementary
- Gene Expression Regulation, Developmental
- Gene Library
- Homeodomain Proteins
- Immunohistochemistry
- In Situ Hybridization
- Microscopy, Confocal
- Models, Biological
- Nerve Tissue Proteins
- Neurons
- Oligonucleotides, Antisense
- Phenotype
- Rhombencephalon