Article
Neonatal lethality, dwarfism, and abnormal brain development in Dmbx1 mutant mice.
Molecular and cellular biology - 1 Sept 2004
Ohtoshi Akihira, Behringer Richard R
Abstract excerpt
Dmbx1 encodes a paired-like homeodomain protein that is expressed in developing neural tissues during mouse embryogenesis. To elucidate the in vivo role of Dmbx1, we generated two Dmbx1 mutant alleles. Dmbx1- lacks the homeobox and Dmbx1z is an insertion of a lacZ reporter gene. Dmbx1z appears to be a faithful reporter of Dmbx1 expression during embryogenesis and after birth. Dmbx1-lacZ expression was detected in...
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