Article
Regional variation in CCR5-Delta32 gene distribution among women from the US HIV Epidemiology Research Study (HERS).
Genes and immunity - 1 Aug 2002
Downer M V, Hodge T, Smith D K, Qari S H, Schuman P, Mayer K H, Klein R S, Vlahov D, Gardner L I, McNicholl J M
Abstract excerpt
The CCR5-Delta32 genotype is known to influence HIV-1 transmission and disease. We genotyped 1301 US women of various races/ethnicities participating in the HIV Epidemiologic Research Study. None was homozygous for CCR5-Delta32. The distribution of heterozygotes was similar in HIV-1 infected and uninfected women. Thirty-seven (11.8%) white, 28 (3.7%) blacks/African Americans (AA), seven (3.3%) Hispanics/Latinas,...
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