Article
CCR5 chemokine receptor genotype frequencies among Puerto Rican HIV-1-seropositive individuals.
Boletin de la Asociacion Medica de Puerto Rico - 1 Jan 2000
Gonzalez S, Tirado G, Revuelta G, Yamamura Y, Lu Y, Nerurkar V R, Yanagihara R
Abstract excerpt
Some individuals remain uninfected by human immunodeficiency virus type 1 (HIV-1), despite multiple sexual contacts with subjects with confirmed HIV-1 infection. Several studies have confirmed that individuals who are homozygous for a 32 base pair (bp) deletion mutation in the chemokine receptor gene CCR5, designated as delta 32/ delta 32, are protected against HIV-1 infection. Heterozygotes of the same chemokine...
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