Article
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.
Antimicrobial agents and chemotherapy - 1 Jun 2006
Bihlmaier C, Welle E, Hofmann C, Welzel K, Vente A, Breitling E, Müller M, Glaser S, Bechthold A
Abstract excerpt
The gram-positive bacterium Streptomyces aureofaciens Tü117 produces the acyclic polyene antibiotic alpha-lipomycin. The entire biosynthetic gene cluster (lip gene cluster) was cloned and characterized. DNA sequence analysis of a 74-kb region revealed the presence of 28 complete open reading fram...
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