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Article

Evolutionary Implications of Bacterial Polyketide Synthases

15 Jun 2005

Abstract excerpt

Polyketide synthases (PKS) perform a stepwise biosynthesis of diverse carbon skeletons from simple activated carboxylic acid units. The products of the complex pathways possess a wide range of pharmaceutical properties, including antibiotic, antitumor, antifungal, and immunosuppressive activities. We have performed a comprehensive phylogenetic analysis of multimodular and iterative PKS of bacteria and fungi and...

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Identifiers

PMID: 15958783
DOI: 10.1093/molbev/msi193

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Evolutionary Implications of Bacterial Polyketide SynthasesPMID 15958783Read ↗

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