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Article

A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.

Molecular & general genetics : MGG - 1 Sept 2000

Räty K, Kunnari T, Hakala J, Mäntsälä P, Ylihonko K

Abstract excerpt

We have cloned and characterized a gene cluster for anthracycline biosynthesis from Streptomyces galilaeus. This cluster, 15-kb long, includes eight genes involved in the deoxyhexose biosynthesis pathway, a gene for a glycosyltransferase and one for an activator, as well as two genes involved in aglycone biosynthesis. Gene disruption targeted to the activator gene blocked production of aclacinomycins in S....

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PMID: 11016846
DOI: 10.1007/s004380000306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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