Article
Low frequency of the ccr5delta32 HIV-resistance allele in mainland China: identification of the first case of ccr5delta32 mutation in the Chinese population.
Scandinavian journal of infectious diseases - 1 Jan 1999
Jiang J D, Wang Y, Wang Z Z, Chen X H, Guo Z M, Pan H L, Bekesi G J, Wang A X, Chen H S
Abstract excerpt
A 32-bp deletion on the CCR5 gene (ccr5delta32) confers resistance to HIV-1 infection. This deletion is common in Caucasians, but rare in Asians. Since the frequency of the ccr5delta32 allele of Chinese in mainland China has been unknown we investigated the ccr5delta32 mutation in a cohort of 407 Chinese people in this area. A 225-bp fragment of CCR5 encompassing the 32-bp region was analysed by PCR,...
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