Article
Proliferation of donor mitochondrial DNA in nuclear transfer calves (Bos taurus) derived from cumulus cells.
Molecular reproduction and development - 1 Apr 2003
Takeda Kumiko, Akagi Satoshi, Kaneyama Kanako, Kojima Toshiyuki, Takahashi Seiya, Imai Hiroshi, Yamanaka Mariko, Onishi Akira, Hanada Hirofumi
Abstract excerpt
In embryos derived by nuclear-transfer (NT), fusion of donor cell and recipient oocyte caused mitochondrial heteroplasmy. Previous studies from other laboratories have reported either elimination or maintenance of donor-derived mitochondrial DNA (mtDNA) from somatic cells in cloned animals. Here we examined the distribution of donor mtDNA in NT embryos and calves derived from somatic cells. Donor mitochondria...
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