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Production and pathogenicity of hepatitis C virus core gene products

1 Jan 2014

Abstract excerpt

Hepatitis C virus (HCV) is a major cause of chronic liver diseases, including steatosis, cirrhosis and hepatocellular carcinoma, and its infection is also associated with insulin resistance and type 2 diabetes mellitus. HCV, belonging to the Flaviviridae family, is a small enveloped virus whose positive-stranded RNA genome encoding a polyprotein. The HCV core protein is cleaved first at residue 191 by the host...

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PMID: 24966583
DOI: 10.3748/wjg.v20.i23.7104

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