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Article

Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity.

Journal of hepatology - 1 Aug 2015

Madejón Antonio, Sheldon Julie, Francisco-Recuero Irene, Perales Celia, Domínguez-Beato Mariela, Lasa Marina, Sánchez-Perez Isabel, Muntané Jordi, Domingo Esteban, García-Samaniego Javier, Sánchez-Pacheco Aurora

Abstract excerpt

BACKGROUND & AIMS: Chronic hepatitis C is a leading cause of chronic liver disease, cirrhosis and hepatocellular carcinoma. DNA methylation and histone covalent modifications constitute crucial mechanisms of genomic instability in human disease, including liver fibrosis and hepatocellular carcinoma. The present work studies the consequences of HCV-induced histone modifications in early stages of infection....

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Source

Identifiers

PMID: 25733156
DOI: 10.1016/j.jhep.2015.02.036

Genes

AURKB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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