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Article

Sequence variability of HCV Core region: important predictors of HCV induced pathogenesis and viral production.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2011

Khaliq Saba, Jahan Shah, Pervaiz Asim

Abstract excerpt

Hepatitis C virus (HCV), a RNA virus belonging to the family Flaviviridae, has been considered to be a significant risk factor in HCV induced liver diseases and development of hepatocellular carcinoma (HCC). Current combination treatment of pegylated interferon-α (PEG-IFN-α) and ribavirin has shown limited efficiency, poor tolerability and significant expense mainly depending upon the HCV genotype. HCV has been...

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Identifiers

PMID: 21292033
DOI: 10.1016/j.meegid.2011.01.017

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