Article
hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer.
Cancer detection and prevention - 1 Jan 2001
Kim J C, Kim H C, Roh S A, Koo K H, Lee D H, Yu C S, Lee J H, Kim T W, Lee H L, Beck N E, Bodmer W F
Abstract excerpt
The pattern of hMLHI and hMSH2 mutations was assessed to identify the genetic correlation between hereditary gastric and colorectal cancers. Four disease groups and their healthy family members were assembled according to the presentation of gastric cancer: FG, familial clustering of gastric cancer (n = 32); CG, family with one or more colorectal and gastric cancers in first-degree relatives (n = 22); HS, seven...
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