Article
Kinetics of CD4 cells after discontinuation of antiretroviral therapy in patients with virological failure and a CD4 cell count greater than 500 cells/microl.
AIDS (London, England) - 26 Jul 2002
Mussini Cristina, Bugarini Roberto, Perno Carlo Federico, Antinori Andrea, Borghi Vanni, Bertoli Ada, D'Arrigo Roberta, Bedini Andrea, Mongiardo Nicola, Cossarizza Andrea, Esposito Roberto
Abstract excerpt
After a median of 37 months on antiretroviral therapy, 16 patients were asked to discontinue treatment instead of changing it. After a median observation time of 10.5 months, most patients experienced a rapid and progressive decrease in their CD4 cell count, even without a high viral load rebound. This decline was unrelated to the CD4 cell count and HIV-RNA values at interruption, but was more profound in...
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