Article
Lamivudine monotherapy in HIV-1-infected patients harbouring a lamivudine-resistant virus: a randomized pilot study (E-184V study).
AIDS (London, England) - 4 Apr 2006
Castagna Antonella, Danise Anna, Menzo Stefano, Galli Laura, Gianotti Nicola, Carini Elisabetta, Boeri Enzo, Galli Andrea, Cernuschi Massimo, Hasson Hamid, Clementi Massimo, Lazzarin Adriano
Abstract excerpt
OBJECTIVE: We compared the immunological and clinical outcomes of lamivudine monotherapy and complete therapy interruption in the treatment of HIV-1-infected patients harbouring lamivudine-resistant virus. METHODS: This 48-week, open-label pilot study randomly assigned HIV-infected patients receiving lamivudine-containing HAART and harbouring the M184V mutation to monotherapy with lamivudine 300 mg once daily...
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