Article
Viral failure in HIV-infected patients with long-lasting viral suppression who discontinued enfuvirtide.
AIDS (London, England) - 11 Sept 2006
Bonjoch Anna, Negredo Eugenia, Puig Jordi, Erkizia Itziar, Puig Teresa, Cabrera Cecilia, Ruiz Lidia, Clotet Bonaventura
Abstract excerpt
The aim of this pilot study was to assess whether enfuvirtide can be discontinued in patients on long-term viral suppression. Eight patients with multidrug-resistant virus were randomly assigned to stop and 10 subjects to continue enfuvirtide. At week 48, viral rebound occurred in five (62.5%) and in no patients, respectively, (P = 0.007). The CD4 cell decrease in failure patients was 5% (P = ns). These results...
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