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Article

Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jul 2005

Campbell Thomas B, Shulman Nancy S, Johnson Steven C, Zolopa Andrew R, Young Russell K, Bushman Lane, Fletcher Courtney V, Lanier E Randall, Merigan Thomas C, Kuritzkes Daniel R

Abstract excerpt

BACKGROUND: Maximum suppression of virus replication is often not achievable for persons infected with multidrug-resistant human immunodeficiency virus type 1 (HIV-1). Available data suggest that lamivudine contributes to partial viral suppression, despite the presence of M184V mutations and high-level phenotypic lamivudine resistance. METHODS: Selective lamivudine withdrawal was studied in 6 subjects who had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15983922
DOI: 10.1086/430709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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