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Article

Clinicopathologic significance of defective DNA mismatch repair in endometrial carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Apr 2006

Black Destin, Soslow Robert A, Levine Douglas A, Tornos Carmen, Chen Shirley C, Hummer Amanda J, Bogomolniy Faina, Olvera Narciso, Barakat Richard R, Boyd Jeff

Abstract excerpt

PURPOSE: Defective DNA mismatch repair is commonly present in sporadic manifestations of gastrointestinal, endometrial, and other cancers. The pathognomonic molecular manifestation of this repair defect is microsatellite instability (MSI). Here, we test the hypothesis that MSI predicts the clinicopathologic features of endometrial carcinoma. PATIENTS AND METHODS: A retrospective cohort of 473 patients treated for...

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Identifiers

PMID: 16549821
DOI: 10.1200/JCO.2005.04.1574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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