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Article

Transcriptional Regulation of Murine β1,4-Galactosyltransferase in Somatic Cells

1 Mar 1996

Abstract excerpt

beta1,4-Galactosyltransferase (beta4-GT) is a constitutively expressed enzyme that synthesizes the beta4-N-acetyllactosamine structure in glycoconjugates. In mammals, beta4-GT has been recruited for a second biosynthetic function, the production of lactose which occurs exclusively in the lactating mammary gland. In somatic tissues, the murine beta4-GT gene specifies two mRNAs of 4. 1 and 3.9 kilobases (kb), as a...

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PMID: 8617793
DOI: 10.1074/jbc.271.9.5131

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