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Article

Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene.

Molecular immunology - 1 Jan 2004

Bruno Maria E C, West Ryan B, Schneeman Tracey A, Bresnick Emery H, Kaetzel Charlotte S

Abstract excerpt

Secretory antibodies protect mucosal surfaces from ingested, inhaled and sexually transmitted pathogens. The polymeric immunoglobulin receptor (pIgR) transports antibodies across mucosal epithelia into external secretions. We and others have identified a region of the human polymeric immunoglobulin receptor gene (locus PIGR) that is sufficient for basal transcriptional activity. An E-Box motif, which binds...

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Share to Gene Expression Regulation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-myc

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Source

Identifiers

PMID: 14644095
DOI: 10.1016/j.molimm.2003.09.004

Genes

PIGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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