Article
Effect of heterogeneous mixing and vaccination on the dynamics of anthelmintic resistance: a nested model.
PloS one - 18 May 2010
Sabatelli Lorenzo
Abstract excerpt
Anthelmintic resistance is a major threat to current measures for helminth control in humans and animals. The introduction of anthelmintic vaccines, as a complement to or replacement for drug treatments, has been advocated as a preventive measure. Here, a computer-based simulation, tracking the dynamics of hosts, parasites and parasite-genes, shows that, depending on the degree of host-population mixing, the...
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