Article
An analysis of the population genetics of potential multi-drug resistance in Wuchereria bancrofti due to combination chemotherapy.
Parasitology - 1 Jul 2007
Schwab A E, Churcher T S, Schwab A J, Basáñez M-G, Prichard R K
Abstract excerpt
Currently, annual mass treatments with albendazole (ABZ) plus ivermectin (IVM) or diethylcarbamazine (DEC) are administered under the Global Programme to Eliminate Lymphatic Filariasis (GPELF). Drug resistance against both ABZ and IVM is prevalent in nematodes of veterinary importance, raising awareness that if anthelmintic resistance were to develop among Wuchereria bancrofti populations, this would jeopardize...
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